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Browsing Nord Open Research Archive by Author "Stork, Michiel"

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    • Bioengineering bacterial outer membrane vesicles as vaccine platform 

      Gerritzen, Matthias J.H.; Martens, Dirk E.; Wijffels, Rene Hubertus; van der Pol, Leo; Stork, Michiel (Journal article; Peer reviewed, 2017)
    • Continuous production of Neisseria meningitidis outer membrane vesicles 

      Gerritzen, Matthias J.H.; Stangowez, Lilli; van de Waterbeemd, Bas; Martens, Dirk E.; Wijffels, Rene Hubertus; Stork, Michiel (Peer reviewed; Journal article, 2019)
      Outer membrane vesicles (OMVs) are nanoparticles secreted by Gram-negative bacteria that can be used for diverse biotechnological applications. Interesting applications have been developed, where OMVs are the basis of drug ...
    • High dissolved oxygen tension triggers outer membrane vesicle formation by Neisseria meningitidis 

      Gerritzen, Matthias J. H.; Maas, Ronald H. W.; Van Den Ijssel, Jan; Van Keulen, Lonneke; Martens, Dirk E.; Wijffels, Rene Hubertus; Stork, Michiel (Journal article; Peer reviewed, 2018)
    • High throughput nanoparticle tracking analysis for monitoring outer membrane vesicle production 

      Gerritzen, Matthias J.H.; Martens, Dirk E.; Wijffels, Rene Hubertus; Stork, Michiel (Journal article; Peer reviewed, 2017)
    • Spontaneously released Neisseria meningitidis outer membrane vesicles as vaccine platform : production and purification 

      Gerritzen, Matthias J.H.; Salverda, Merijn LM; Martens, Dirk E.; Wijffels, Rene Hubertus; Stork, Michiel (Peer reviewed; Journal article, 2019)
      Outer membrane vesicles (OMVs) are nanoparticles produced by Gram-negative bacteria that can be used as vaccines. The application of OMVs as vaccine component can be expanded by expressing heterologous antigens on OMVs, ...
    • Sulfate depletion triggers overproduction of phospholipids and the release of outer membrane vesicles by Neisseria meningitidis 

      Gerritzen, Matthias J.H.; Martens, Dirk E.; Uittenbogaard, Joost P.; Wijffels, Rene Hubertus; Stork, Michiel (Peer reviewed; Journal article, 2019)
      Outer membrane vesicles (OMVs) produced by bacteria are interesting vaccine candidates. OMVs are nanoparticles that contain many immunogenic components, are self-adjuvating, and non-replicative. Despite recent insights in ...

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