Browsing Nord Open Research Archive by Author "Vaage, Ingvar Jarle"

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Isolated Plin5-deficient cardiomyocytes store less lipid droplets than normal, but without increased sensitivity to hypoxia

Li, Yuchuan; Torp, May-Kristin; Norheim, Frode; Khanal, Prabhat; Kimmel, Alan R.; Stensløkken, Kåre-Olav; Vaage, Ingvar Jarle; Dalen, Knut Tomas (Peer reviewed; Journal article, 2020)

Plin5 is abundantly expressed in the heart where it binds to lipid droplets (LDs) and facilitates physical interaction between LDs and mitochondria. We isolated cardiomyocytes from adult Plin5+/+ and Plin5-/- mice to study ...
Plin2 deletion increases cholesteryl ester lipid droplet content and disturbs cholesterol balance in adrenal cortex

Li, Yuchuan; Khanal, Prabhat; Norheim, Frode; Hjorth, Marit; Bjellaas, Thomas; Drevon, Christian A; Vaage, Ingvar Jarle; kimmel, Alan; Dalen, Knut Tomas (Peer reviewed; Journal article, 2021)

Cholesteryl esters (CEs) are the water-insoluble transport and storage form of cholesterol. Steroidogenic cells primarily store CEs in cytoplasmic lipid droplet (LD) organelles, as contrasted to the majority of mammalian ...