Blar i Nord Open Research Archive på forfatter "Skjærven, Kaja Helvik"
-
Associations Between Behavioral Effects of Bisphenol A and DNA Methylation in Zebrafish Embryos
Olsvik, Pål Asgeir; Whatmore, Paul; Penglase, Sam J.; Skjærven, Kaja Helvik; d'Auriac, Marc Anglès; Ellingsen, Ståle (Journal article; Peer reviewed, 2019)Endocrine-disrupting contaminants have been associated with aberrant changes in epigenetic pathways in animals. In this study, zebrafish embryos were exposed bisphenol A (BPA) to search for associations between behavior ... -
Metabolic and molecular signatures of improved growth in Atlantic salmon (Salmo salar) fed surplus levels of methionine, folic acid, vitamin B6 and B12 throughout smoltification
Adam, Anne-Catrin; Saito, Takaya; Espe, Marit; Whatmore, Paul; Fernandes, Jorge Manuel de Oliveira; Vikeså, Vibeke; Skjærven, Kaja Helvik (Peer reviewed; Journal article, 2021) -
Micronutrient supplementation affects DNA methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes
Saito, Takaya; Whatmore, Paul; Taylor, John F.; Fernandes, Jorge Manuel de Oliveira; Adam, Anne-Catrin; Tocher, Douglas R.; Espe, Marit; Skjærven, Kaja Helvik (Peer reviewed; Journal article, 2022) -
Micronutrient supplementation affects transcriptional and epigenetic regulation of lipid metabolism in a dose-dependent manner
Saito, Takaya; Whatmore, Paul; Taylor, John F.; Fernandes, Jorge Manuel de Oliveira; Adam, Anne-Catrin; Tocher, Douglas R.; Espe, Marit; Skjærven, Kaja Helvik (Peer reviewed; Journal article, 2020) -
Ocean warming shapes embryonic developmental prospects of the next generation in Atlantic cod
Skjærven, Kaja Helvik; Alix, Maud; Kleppe, Lene; Fernandes, Jorge Manuel de Oliveira; Whatmore, Paul; Nedoluzhko, Artem; Andersson, Eva; Kjesbu, Olav Sigurd (Peer reviewed; Journal article, 2024)Although early embryonic protein production relies exclusively on maternal molecules such as messenger RNAs (mRNAs) incorporated into ovarian follicles, knowledge about any thermally induced, intergenerational effects is ... -
One-carbon metabolism nutrients impact the interplay between DNA methylation and gene expression in liver, enhancing protein synthesis in Atlantic salmon
Saito, Takaya; Espe, Marit; Vikeså, Vibeke; Bock, Christoph; Thomsen, Tårn H.; Adam, Anne-Catrin; Fernandes, Jorge Manuel de Oliveira; Skjærven, Kaja Helvik (Peer reviewed; Journal article, 2024)Supplementation of one-carbon (1C) metabolism micronutrients, which include B-vitamins and methionine, is essential for the healthy growth and development of Atlantic salmon (Salmo salar). However, the recent shift towards ... -
Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring
Skjærven, Kaja Helvik; Jakt, Lars Martin; Fernandes, Jorge Manuel de Oliveira; Dahl, John Arne; Adam, Anne-Catrin; Klughammer, Johanna; Bock, Christoph; Espe, Marit (Journal article; Peer reviewed, 2018)Micronutrient status of parents can affect long term health of their progeny. Around 2 billion humans are affected by chronic micronutrient deficiency. In this study we use zebrafish as a model system to examine morphological, ... -
Parental vitamin deficiency affects the embryonic gene expression of immune-, lipid transport- and apolipoprotein genes
Skjærven, Kaja Helvik; Jakt, Lars Martin; Dahl, John Arne; Espe, Marit; Aanes, Håvard; Hamre, Kristin; Fernandes, Jorge M.O. (Journal article; Peer reviewed, 2016) -
Profiling DNA methylation patterns of zebrafish liver associated with parental high dietary arachidonic acid
Adam, Anne-Catrin; Lie, Kai Kristoffer; Whatmore, Paul; Jakt, Lars Martin; Moren, Mari; Skjærven, Kaja Helvik (Journal article; Peer reviewed, 2019)